This month’s Orphanews has an editorial about “Building a better future for rare diseases: campaigns launched at European and international level“. It also announces that the ORPHAcodes: Orphanet Nomenclature Pack 2021 is now available and has news about Solve-RD, the European Project that adresses the needs of unsolved RD cases, announces the opening of nominations for the EURORDIS Black Pearl Awards 2022 and other subjects.