Vincenzo Silani is Professor of Neurology and Director of the Department of Neuroscience and Laboratory of Neuroscience at the IRCCS Istituto Auxologico Italiano – University of Milan Medical School. Director of the “Dino Ferrari” Center for Neuromuscular and Neurodegenerative Disease in Auxologico since 2002, he was post-doctoral fellow in the Department of Neurology at the Baylor College of Medicine, Houston, USA (1979-1981), and then Visiting Professor of Neurology at Baylor (1999). He was co-chairman (2002-2005) and chairman (2005-2007) of the European ALS Consortium (EALSC); co-director of the European Academy of Neurology Subspeciality Panel for ALS and Frontotemporal Dementia (2003-2019); elected as FEAN and FAAN. He is internationally recognized as a leading scientist in ALS/FTD and he established an ALS/FTD Centre in Milan with a large database of familiar and sporadic cases. He founded the SLAGEN Consortium (2010) for genetics and he is active in ENCALS, Project MinE, TRICALS, and NEALS. He largely contributed in defining the expression of new genes in both SALS and FALS, investigating the functional role of TDP43, FUS/TLS, and C9ORF72 using human motor neurons derived from iSCPs. He is author of more than 400 scientific publications and he has been P.I. of several clinical trials. He is since 2017 part of the ERN EURO-NMD and recently appointed as chair and co-chair of the ERN EURO-NMD expert working group on motor neuron diseases.