Prof Valeria Tiranti

• Valeria Tiranti, is Deputy Scientific director of the Fondazione IRCCS Istituto Neurologico Carlo Besta and she is responsible for the Lab of Molecular Pathology of Mitochondrial Disorders, Unit of Medical Genetics. She has a long−standing expertise in mitochondrial and metabolic disorders, including identification of disease genes, biochemical evaluation of the respiratory chain activities, molecular and cellular biology, and identification of pathogenetic mechanisms of diseases. Her group performed the characterization of different mouse models and attempted pharmacological treatments in some of them. Recently, her group started generating 2D (induced pluripotent stem cells, iPSCs) and 3D (brain organoids) in vitro models from PBMC and fibroblasts of patients affected by mitochondrial neurodegenerative diseases and genetic optic atrophy.