Dr Pierre Carlier is a leading specialist in magnetic resonance imaging and spectroscopy of muscle with a particular interest in its development as a quantitative outcome measure. One of the main goals of Pierre’s lab at the Institut de Myologie is to move from qualitative and semi-quantitative evaluation to truly quantitative imaging measurements, which are essential to ensure the clinical relevance of high-technology imaging procedures. Developing and refining these quantitative techniques may enable the detection of very early and pre-clinical signs of a positive response to treatment, thus making MRI and MRS potentially attractive outcome measures in trials. Pierre is developing standard operating procedures for the use of certain quantitative techniques and is engaged in numerous research projects further developing MRI&S as a non-invasive diagnostic tool and outcome measure.
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