In this second edition of MitoPorto (2018, July 13th) the emphasis will be on mitochondrial evolution, metabolism and disease. Nevertheless, they welcome abstracts and communications from scientists with a multidisciplinary interest in mitochondrial research (e.g. in the context of neuroscience, cancer, genetics, etc.). The program will combine keynote lectures with oral communications selected from the abstracts. Poster sessions will allow participants to discuss their work with fellow scientists and extend collaborative networks.